Nonequilibrium stresses and fluxes: compositional organization at the cell surface and organelle morphodynamics Madan Rao, India
Chair: Juan M. R. Parrondo, Spain
10:00-12:45
LIPID AND LIPIDOME Chairs:John Seddon, UK and Francisco Monroy, Spain Invited speakers: 10:00 Membrane remodeling by the amyloidogenic peptide IAPP: surface crowing relevance Manuel Prieto, Portugal 10:30 How the globoside Gb3 partitions in phase-separated membranes. Claudia Steinem, Germany
11:00-11:30 COFFEE BREAK
11:30 Curvature rigidity of asymmetric and differentially stressed membranes Markus Deserno, USA
Short Talks: 12:00 Formation of membrane domains: insight from simulations on different scales Andreas Heuer, Germany 12:15 Monte Carlo and molecular dynamics simulations to explain biomembrane meso-patterning by a composition-curvature coupling mechanism Julie Cornet, France 12:30 Biophysical properties of 1-deoxyceramides in ordered and disordered bilayers Felix M Goñi, Spain
MADRID
10:00-12:45
BIG DATA IN BIOPHYSICS Chairs:Remy Monasson, France and Alfonso Valencia, Spain Invited speakers: 10:00 A systems approach to understanding the allosteric mechanism of pyruvate kinase M2 Franca Fraternali, UK 10:30 Statistical mechanics of protein evolution: From models to algorithms Ugo Bastolla, Spain
11:00-11:30 COFFEE BREAK
11:30 Combining imaging and gene expression data in mathematical models for immuno-oncology Vera Pancaldi, France
Short Talks: 12:00 Real-time dynamic changes in serum metabolome during the anticancer treatment by means of NMR-based metabolomics Lukasz Boguszewicz, Poland 12:15 Decrypting interaction fingerprints in protein molecular surfaces Bruno Correia, Switzerland 12:30 Bayesian inference and machine learning approaches to determine protein copy number from localization microscopy Carlo Manzo, Spain
ROMA
10:00-12:45
INSTRUCT-ERIC: INTEGRATING ACCESS TO BIOPHYSICS AND STRUCTURAL BIOLOGY IN EUROPE Chair:Ray Owens, UK
Invited speakers: 10:00 Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity Rob Gilbert, UK 10:30 NMR-based hybrid approaches for cellular structural biology Marc Baldus, Netherlands
11:00-11:30 COFFEE BREAK
11:30 Towards High Throughput cryoEM data acquisition and processing, assuring reproducibility Jose-Maria Carazo, Spain
Short Talks: 12:00 Access to structural biology and biophysics technologies through Instruct-ERIC Naomi Gray, UK 12:15 Crystal structures of bacteriophage receptor binding proteins Mark J. Van Raaij, Spain 12:30 The Cryo-EM Structure of a Non-toxic Greek Key Oligomer of Alpha Synuclein Ritobrita Chakraborty, India
PARIS
10:00-12:45
LIQUID-LIQUID PHASE SEPARATION IN BIOLOGICAL SYSTEMS Chair:Mauro della Serra, Italy Invited speakers: 10:00 Bacterial division protein phase-separated condensates: biochemical and functional consequences (Bruker SBE Prize) German Rivas, Spain 10:30 Light controlled cytoplasmic transport to probe cellular organization Mortiz Kreysing, Germany
11:00-11:30 COFFEE BREAK
11:30 Multivalency of proteins in cellular phase separation Samuel Safran, Israel
Short Talks: 12:00 General sol to gel transition of liquid-liquid phase separated protein under shear Yi Shen, UK 12:15 Recapitulation of nucleocytoplasmic transport with phase-separation of engineered protein repeats Sheung Chun Ng, Germany 12:30 Protein phase transition: from biology towards new dynamic protein materials Paolo Arosio, Switzerland