Overcoming the multiscale simulation challenge for biomolecular systems Gregory Voth, USA
Chair: Ilpo Vattulainen, Finland
10:00-12:45
BIOMOLECULAR SIMULATION I Chairs:Claudio Soares, Portugal and Ilpo Vattulainen, Finland Invited speakers: 10:00 Deep learning for molecular biophysics Frank Noe, Germany 10:30 Sculpting cell membranes by protein nanomachines. Andela Saric, UK
11:00-11:30 COFFEE BREAK
11:30 Pentameric ligand-gated ion channels: new crystal structures and MD simulations Marc Delarue, France
Short Talks: 12:00 Automated cryo-EM structure refinement using correlation-driven molecular dynamics Maxim Igaev, Germany 12:15 Aβ peptides and β-sheet breakers. A coarse grained molecular dynamics approach using GO-Martini Aishwarya Dhar, Italy 12:30 Effect of pH on the influenza fusion peptide structure and activity: A constant-pH molecular dynamics approach Diana Lousa, Portugal
MADRID
10:00-12:45
MACROMOLECULAR COMPLEXES Chairs:Tony Wilkinson, UK and Irene Diaz-Moreno, Spain Invited speakers: 10:00 Recent insights into the peptide-loading complex machinery Simon Trowitzch, Germany 10:30 LUBAC and linear ubiquitin chains: novel tools to study immune signalling Katrin Rittinger, UK
11:00-11:30 COFFEE BREAK
11:30 Analysing cryoEM data quality in the post resolution revolution era: Validity criteria José M. Carazo, Spain
Short Talks: 12:00 Histone tails in nucleosome: fuzzy interaction with DNA Sevastyan Rabdano, Russia 12:15 New protein-protein interaction modulators for the therapeutic regulation of synapse dysfunction in neurodevelopmental disorders and neurodegeneration Maria Jose Sanchez-Barrena, Spain 12:30 Structural characterisation of tissue-derived, disease-associated polymers of alpha-1-antitrypsin using conformation-selective antibodies and single-particle reconstructions from electron microscopy images James Irving, UK
ROMA
10:00-12:45
BIOPHYSICS OF MEMBRANE OXIDATION Chairs:Manuel Prieto, Portugal and Rosangela Itri, Brazil
Invited speakers: 10:00 Photosensitized oxidation of lipid membranes: yields and rates of chemical and physical changes Mauricio da Silva, Brazil 10:30 Achievements, challenges and hopes in the biophysical analysis of oxidised (phospho)lipids Ana Reis, Portugal
11:00-11:30 COFFEE BREAK
11:30 Oxysterols and Truncated Oxidized Phospholipids in Model Membranes Martin Hof, Czech Republic
Short Talks: 12:00 Lipids as substrates and dynamic activators: pro-apoptotic lipid peroxidation at the mitochondrial membrane surface Patrick Van Der Wel, Netherlands 12:15 The effect of oxidised cholesterol on model red blood cell membranes Paul Smith, UK 12:30 Lipid curvature modulates function of mitochondrial membrane proteins Olga Jovanovic, Austria
Invited speakers: 10:00 Eco-evolutionary dynamics during Escherichia coli colonization of the mouse gut Isabel Gordo, Portugal 10:30 Evolutionary Biology of Cell Division: Integrating Quantitative Genetics and Cellular Biophysics Daniel Needelman, USA
11:00-11:30 COFFEE BREAK
11:30 Universal properties of genotype-phenotype maps Sebastian Ahnert, UK
Short Talks: 12:00 ScarTrace: CRISPR/Cas9-mediated clonal tracing in zebrafish embryonic development and regeneration Anna Alemany, The Netherlands(Premio Antalgenics SBE) 12:15 Rare beneficial mutations cannot halt Muller's ratchet in spatial populations Su-Chan Park, South Korea 12:30 Exploring phenotypic variability of bacteria using microfluidic cell traps Ágnes Ábrahám, Hungary
