Programme
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13:30-18:00 ONSITE REGISTRATION 15:00-17:00 EBSA EC FIRST MEETING (CLOSED) 17:30-18:00 WELCOME ADDRESS 18:00-19:00 PLENARY LECTURE
Harnessing Evolution to create new medicines
Sir Gregory Paul Winter
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08:00-18:00 REGISTRATION 09:00-09:45 PLENARY LECTURE
Eukaryotic organelles: deciphering their interdependency, structure and dynamics with new imaging technologies
Jennifer Lippincott-Schwartz, USA10:00-12:45 PROTEIN FOLDING
Chairs:
Ana Azuaga, Spain
Jacqueline Cherfils, France
Confirmed speakers:
- Understanding alpha-synuclein amyloid self-assembly and its associated toxicity
Nunilo Cremades, Spain - Dodging the crisis of folding proteins with non-trivial topology - new challenges.
Joanna Sulkowska, Powland - The structural determinants of the toxicity of misfolded protein oligomers associated with neurodegenerative diseases
Fabrizio Chiti, Italy
11:00-11:30 COFFEE BREAK12:45-14:30 LUNCH AND POSTER SESSION 14:30-15:15 PLENARY LECTURE
Shaping Membranes with Proteins and Cytoskeleton: Deciphering Mechanisms with Reconstituted Systems
Patricia Bassereau, France15:15-16:00 AVANTI PRIZE CONFERENCE
Control of organelle dynamics by membrane curvature and lipid unsaturation
Bruno Antonny, France16:00-16:30 EBSA YOUNG INVESTIGATOR AWARD 16:30-19:15 MEMBRANE STRUCTURE AND DYNAMICS
Chairs:
Claudia Steinem, Germany
Felix Goñi, Spain
Confirmed speakers:
- Lessons Learned from Complex Mimics of Biological Membranes
Georg Pabst, Austria - Regulating the dynamic interactions between herpes simplex viruses and cell-surface glycosaminoglycans
Marta Bally, Sweden - IQGAP1 links phosphoinositide signaling to the cytoskeleton and promotes cytoskeleta reorganization
Arne Gericke, USA
3 ORAL PRESENTATIONS
16:30-17:30 COFFEE BREAK - Understanding alpha-synuclein amyloid self-assembly and its associated toxicity
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10:00-12:45 DNA ARCHITECTURE
Chairs:
Masaki Sasai, Japan
Helmut Schiessel, Netherlands
Confirmed speakers:
- DNA release from histones in nucleosome core particles: measurements and models
Lois Pollack, USA - Gene control with a “twist”: Exploring the dynamic chromatin landscape
Beat Fierz, Switzerland - Kazuhiro Maeshima, Japan
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-14:30 LUNCH AND POSTER SESSION 16:30-19:15 CELLULAR PROLIFERATION
Chairs:
Herbert Levine, USA
Berenike Maier, Germany
Confirmed speakers:
- Dynamics of bacterial swarms and biofilms
Knut Drescher, Germany - Biophysical Concepts Applied to Tumor Progression
Herbert Levine, USA - How molecular forces shape bacterial biofilms
Berenike Maier, Germany
3 ORAL PRESENTATIONS
16:30-17:30 COFFEE BREAK - DNA release from histones in nucleosome core particles: measurements and models
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10:00-12:45 BIOPHYSICS OF CYTOSKELETON
Chairs:
Marisela Velez, Spain
Andreas Janshoff, Germany
Confirmed speakers:
- Mind the gap: polyampholytes meet the neuronal skeleton
Roy Beck, Israel - Marleen Dogterom, The Netherlands
- The spindle is a composite of two permeating polar gels
Jan Brugués, Germany
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-14:30 LUNCH AND POSTER SESSION 16:30-19:15 NON-EQUILIBRIUM PHYSICS
Chairs:
Udo Seifert, Germany
Felix Ritort, Spain
Confirmed speakers:
- Ivan Lopez-Montero, Spain
- Quantifying and modelling active motion in biological systems
Timo Betz, Germany - Dynamics of nanoparticle and virus uptake at cell membranes
Ulrich Schwarz, Germany
3 ORAL PRESENTATIONS
16:30-17:30 COFFEE BREAK - Mind the gap: polyampholytes meet the neuronal skeleton
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10:00-12:45 MECHANOBIOLOGY
Chairs:
Malgorzata Lekka, Poland
Pere Roca-Cusachs, Spain
Confirmed speakers:- Mechanically and biochemically induced pathways regulating integrin-dependent cell adhesion
Daniel Mueller, Switzerland - Molecular to cellular mechanics at short timescales
Felix Rico, France - Mechanosensitive actomyosin network dynamics and migration plasticity in 3D environments
Verena Ruprecht, Spain
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:30-19:15 TRAFFICKING AND SIGNALLING
Chairs:
Ana Garcia-Saez, Germany
Carlo Manzo, Spain
Confirmed speakers:
- Systematic superresolution analysis of endocytosis reveals an actin nucleation nano-template that drives efficient vesicle formation
Jonas Ries, Germany - Davide Calebiro, UK
- Cryo-EM structural analysis of focal adhesion machinery
Naoko Mizuno, Germany
3 ORAL PRESENTATIONS
16:30-17:30 COFFEE BREAK - Mechanically and biochemically induced pathways regulating integrin-dependent cell adhesion
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08:00-18:00 REGISTRATION 09:00-09:45 PLENARY LECTURE
Gregory Voth, USA10:00-12:45 BIOMOLECULAR SIMULATION I
Chairs:
Claudio Soares, Portuga
Ilpo Vattulainen, Finland
Confirmed speakers:
- Frank Noe, Germany
- Sculpting cell membranes by protein nanomachines
Andela Saric, UK - Marc Delarue, France
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 13:00-15:00 MEETING OF EBSA Presidents 15:00-15:45 PLENARY LECTURE
Cryo-EM to visualize structure and dynamics of complex biological macromolecular assemblies
Eva Nogales, USA15:45-16:15 PRIZES IUPAP 1&2 16:15-19:15 PROTEIN STRUCTURE AND FUNCTION
Chairs:
Mark Baldus, Netherlands
Juan Hermoso, Spain
Confirmed speakers:
- Pedro Alzari, France
- Molecular Basis for the Extra-Mitochondrial Roles of Cytochrome c in Cell Life and Death
Miguel Angel de la Rosa, Spain
- Atomistic Simulation of Biomolecular Function: Ribosomal Translation and Ligand Binding Heterogeneity
Helmut Grubmueller, Germany
3 ORAL PRESENTATIONS
17:30-18:00 COFFEE BREAK19:15-20:15 NATIONAL ASSEMBLIES -
10:00-12:45 MACROMOLECULAR COMPLEXES
Chairs:
Tony Wilkinson, UK
Irene Diaz-Moreno, Spain
Confirmed speakers:
- Recent insights into the peptide-loading complex machinery
Simon Trowitzch, Germany - LUBAC and linear ubiquitin chains: novel tools to study immune signalling
Katrin Rittinger, UK - Analysing cryoEM data quality in the post resolution revolution era: Validity criteria
José M. Carazo, Spain
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:30-19:15 GENE NETWORK DYNAMICS AND SIGNALING
Chairs:
Marta Ibañez, Spain
Jan Brugues, Germany
Confirmed speakers:
- Stochastic Turing patterns in the development of a one-dimensional organism
Joel Stavans, Israel - Human time vs. Mouse time: in vitro segmentation clock as a model system
Miki Ebisuya, Spain - Distinguishing dormant from dead cells
Hyun Youk, The Netherlands
3 ORAL PRESENTATIONS
17:30-18:00 COFFEE BREAK - Recent insights into the peptide-loading complex machinery
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10:00-12:45 EVOLUTIONARY DYNAMICS
Chairs:
Susanna Manrubia, Spain
Liedewij Laan, Netherlands
Confirmed speakers:
- Isabel Gordo, Portugal
- Daniel Needelman,USA
- Universal properties of genotype-phenotype maps
Sebastian Ahnert, UK
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:30-19:15 NEW FRONTIERS IN BIOIMAGING
Chair:
Silvia Caponi, Italy
Christian Eggelin, Germany
Confirmed speakers:
- Ilaria Testa,Sweden
- Gail McConnell, UK
- Brillouin Microscopy for cell and tissue biomechanics
Giuliano Scarcelli, USA
3 ORAL PRESENTATIONS
17:30-18:00 COFFEE BREAK - Isabel Gordo, Portugal
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10:00-12:45 BIOPHYSICS OF MEMBRANE OXIDATION
Chairs:
Manuel Prieto, Portugal
Rosangela Itri, Brazil
Confirmed speakers:
- Photosensitized oxidation of lipid membranes: yields and rates of chemical and physical changes
Mauricio da Silva - Achievements, challenges and hopes in the biophysical analysis of oxidised (phospho)lipids
Ana Reis - Oxysterols and Truncated Oxidized Phospholipids in Model Membran
Martin Hof
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:30-19:15 CELL MEMBRANE BIOPHYSICS (Sponsorized by CPL, Elsevier)
Chairs:
Edgard Koijmann, USA
Gemma Fabries, Spain
Confirmed speakers:
- Cholesterol modulation of nicotinic acetylcholine receptor single molecule and nanocluster trajectories
Francisco Barrantes, Argentina - Morphology of Membrane Contact Sites Contributes to the Regulation of the Phosphatidylinositol Cycle
Richard Epand, Canada - Valerian Kagan, USA
3 ORAL PRESENTATIONS
17:30-18:00 COFFEE BREAK - Photosensitized oxidation of lipid membranes: yields and rates of chemical and physical changes
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08:00-18:00 REGISTRATION 09:00-09:45 PLENARY LECTURE 6
Titin folding powers muscle contractio
Julio Fernandez, USA10:00-12:45 MECHANISMS OF MEMBRANE PROTEINS
Chairs:
Manuela Pereira, Portugal
Antonio Ferrer, Spain
Confirmed speakers:
- Factors affecting Ion Permeation through K+-Channels
Camen Domene, UK - The first human lacking functional TRPV1 channel: Implications onTRPV1 functions in nociception
Baruk Minke, Israel - Optoelectrical dynamics of BK channel activation
Teresa Giraldez, Spain
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 15:00-16:15 NEW AND NOTABLE
Chair:
Anthony Watts, UK
Maria Garcia-Parajo, Spain
Confirmed speakers:
- Trevor Forsyth
- Cryo-EM of Helical Polymers at Near Atomic Resolution Yields Surprises: From Microbial Nanowires to Indestructible Pili
Edward H. Egelman, USA - Kheya Senguptaa, France
16:15-19:00 BIOMOLECULAR SIMULATION II
Chairs:
Claudio Soares, Portugal
Ilpo Vattulainen, Finland
Confirmed speakers:
- Advances in Multiscale Simulation of DNA
Modesto Orozco, Spain - Nanoparticle-bio interactions: the role of interface composition, conformation and softness
Giulia Rossi, Italy - Emad Tajkhorshid, USA
3 ORAL PRESENTATIONS
17:15-17:45 COFFEE BREAK19:00-20:00 EBSA GENERAL ASSEMBLY - Factors affecting Ion Permeation through K+-Channels
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10:00-12:45 SINGLE MOLECULE BIOPHYSICS
Chairs:
Nuno Santos, Portugal
David Rueda, UK
Confirmed speakers:
- The mechanical stability of proteins regulates their translocation rate into the cell nucleus
Sergi Garcia-Manyes, UK - Mechanosensitive states of the giant muscle protein titin
Miklos Kellermayer - María Carmo-Fonseca
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:15-19:00 LIVE IMAGING AND OPTICAL MICROSCOPY
Chair:
Sussane Fenz, Germany
Suliana Manley, Switzerland
Confirmed speakers:
- Faster and better: taking localisation microscopy into live cells
Susan Cox, UK - A Multi Messenger microscope to paint chromatin in cells.
Alberto Diaspro, Italy - Looking into the nursery of platelets: Imaging of the bone marrow in vivo, in vitro and in silico
Katrin Heinze, Germany
3 ORAL PRESENTATIONS
17:15-17:45 COFFEE BREAK - The mechanical stability of proteins regulates their translocation rate into the cell nucleus
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10:00-12:45 BIOPHYSICS OF IMMUNE RESPONSE
Chairs:
Jean Marie Ruysschaert, Belgium
Mario Castro, Spain
Confirmed speakers:
- Andrea Ablasser, Switzerland
- Cheng Zhu, USA
- The role of oligomeric scaffolds in inflammatory signal transduction though Toll-like receptors and MyD88
Nick Gay, UK
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 16:15-19:00 ACTIVE MATTER AND BIOLOGICAL SELF-ORGANIZATION
Chair:
Sriram Ramaswamy, India
Ramin Golestanian, Germany
Confirmed speakers:
- Active Polymers and Membranes
Gerhard Gompper, Germany - The microtubule/kinesin system: A versatile realization of an active nematic
Francesc Sagues, Spain - Silke Henkes, UK
3 ORAL PRESENTATIONS
17:15-17:45 COFFEE BREAK -
16:15-19:00 IONIC LIQUIDS AND BIOMOLECULES
Chairs:
Hans-Joachim Galla, Germany
Pietro Ballone, Ireland
Confirmed speakers:
- Ionic liquids in bio-systems: from model biomembranes to living cell
Antonio Benedetto, Italy - Aqueous Ionic Liquids: Consequences for Biological Stabilities
Jens Smiatek, Germany - Valentine Ananikov, Russia
17:15-17:45 COFFEE BREAK - Ionic liquids in bio-systems: from model biomembranes to living cell
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08:00-18:00 REGISTRATION 09:00-09:45 PLENARY LECTURE 7
Nonequilibrium stresses and fluxes: composition organization at the cell surface and organelle morphodynamics
Madan Rao, India10:00-12:45 LIPID AND LIPIDOME
Chairs:
John Seddon, UK
Francisco Monroy, Spain
Confirmed speakers:
- Membrane remodeling by the amyloidogenic peptide IAPP: surface crowing relevance
Manuel Prieto, Portugal - How the globoside Gb3 partitions in phase-separated membranes
Claudia Steinem, Germany - Curvature rigidity of asymmetric and differentially stressed membranes
Markus Deserno, USA
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 14:00-15:00 EBSA EC SECOND MEETING 15:00-17:45 MOLECULAR MOTORS
Chair:
Christoph Schmidt, USA
Jose Carrascosa, Spain
Confirmed speakers:
- Cooperative Functions of Molecular Motor Assemblies
Shin'Ichi Ishiwata, Japan - A molecular hurdle race: How does DNA polymerase deal with SSBs stably bound to the template?
Borja Ibarra, Spain - Peter Bieling Germany
3 ORAL PRESENTATIONS
16:00-16:30 COFFEE BREAK18:00-19:00 CLOSING PLENARY LECTURE
Stefan Hell, Germany19:00-19:30 CLOSING CEREMONY 21:00 CONGRESS DINNER - Membrane remodeling by the amyloidogenic peptide IAPP: surface crowing relevance
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10:00-12:45 BIG DATA IN BIOPHYSICS
Chairs:
Remy Monasson, France
Alfonso Valencia, Spain
Confirmed speakers- A systems approach to understanding the allosteric mechanism of pyruvate kinase M2
Franca Fraternali, UK - Data-driven models of protein sequence landscapes : inference, 3D structure prediction and protein design
Martin Weigt, France - Combining imaging and gene expression data in mathematical models for immuno-oncology
Vera Pancaldi, France
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 15:00-17:45 TISSUE BIOPHYSICS AND MORPHOGENESIS
Chair:
Francoise Brochard-Wyart, France
Stephan Grill, Germany
Confirmed speakers:
- Forming, watching and stressing organoids
Pierre Nassoy, France - Physics of epithelial folds and flows
Guillaume Salbreux, UK - Bacterial colonies as active droplets - from single cells to continuum theory
Vasily Zaburdaev, Germany
3 ORAL PRESENTATIONS
16:00-16:30 COFFEE BREAK - A systems approach to understanding the allosteric mechanism of pyruvate kinase M2
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10:00-12:45 LIQUID-LIQUID PHASE SEPARATION IN BIOLOGICAL SYSTEMS
Chairs:
Rumiana Dimova, Germany
Mauro della Serra, Italy
Confirmed speakers:
- German Rivas, Spain
- Mortiz Kreysing, Germany
- Multivalency of proteins in cellular phase separation
Samuel Safran, Isreal
3 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK12:45-15:00 LUNCH AND POSTER SESSION 15:00-17:45 EMERGING BREAKTHROUGH MOLECULAR-SCALE BIOPHYSICS METHODOLOGIES (sponsored by COST Action MOBIEU – CA15126)
Chair:
Patrick England, France
Isabel Alves, France
Confirmed speakers:- Perdita Barran, UK
- Access to Atomic Resolution Structural Information of Homor-Repeats: The Huntingtin Case
Pau Bernado, France
- Peter Hinterdorfer, Austria
16:00-16:30 COFFEE BREAK -
10:00-12:45 INSTRUCT-ERIC: INTEGRATING ACCESS TO BIOPHYSICS AND STRUCTURAL BIOLOGY IN EUROPE
Chair:
Ray Owens, UK
Confirmed speakers:
- Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity
Rob Gilbert, UK - NMR-based hybrid approaches for cellular structural biology
Marc Baldus, The Netherlands - Towards High Throughput cryoEM data acquisition and processing, assuring reproducibility
Jose-Maria Carazo, Spain - Access to structural biology and biophysics technologies through Instruct-ERIC
Naomi Gray, UK
2 ORAL PRESENTATIONS
11:00-11:30 COFFEE BREAK - Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity
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