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AUDITORIUM
09:00 PLENARY LECTURE
Eukaryotic organelles: deciphering their interdependency, structure and dynamics with new imaging technologies
Jennifer Lippincott-Schwartz, USA

Chair: María García-Parajo, Spain
10:00-12:45



PROTEIN FOLDING
Chairs: Ana Azuaga, Spain and  Jacqueline Cherfils, France

I
nvited speakers:
10:00
Understanding alpha-synuclein amyloid self-assembly and its associated toxicity

Nunilo Cremades, Spain

10:30
Dodging the crisis of folding proteins with non-trivial topology - new challenges.

Joanna Sulkowska, Powland

11:00-11:30 COFFEE BREAK

11:30
The structural determinants of the toxicity of misfolded protein oligomers associated with neurodegenerative diseases

Fabrizio Chiti, Italy

Short Talks:
12:00
Prion soft amyloid core driven self-assembly of globular proteins into bioactive nanofibrils

Weiqiang Wang, Spain
12:15
Unravelling the details of the conformational cycle of the Hsp90 chaperone

Katarzyna Tych, Germany
12:30
Strategically positioned slow codons support protein folding

Michal Perach, Israel
MADRID
10:00-12:45



DNA ARCHITECTURE AND GENE REGULATION
Chairs: Masaki Sasai, Japan and Helmut Schiessel, Netherlands

I
nvited speakers:
10:00
DNA release from histones in nucleosome core particles: measurements and models

Lois Pollack, USA
10:30
Gene control with a “twist”: Exploring the dynamic chromatin landscape

Beat Fierz, Switzerland

11:00-11:30 COFFEE BREAK

11:30
Chromosome organization in living human cells revealed by single nucleosome imaging

Kazuhiro Maeshima, Japan

Short Talks:
12:00
Non-specific action of polyamines leads to specific changes in structure and function of DNA

Takashi Nishio, Japan
12:15
Simulating the binding of Pioneer Transcription Factors to the nucleosome

Jan Huertas, Germany
12:30
Dependence of DNA Persistence Length on Ionic Strength and Ion Type
Catherine Tardin, France
ROMA
10:00-12:45



MECHANOBIOLOGY
Chair: Pere Roca-Cusachs, Spain

I
nvited speakers:
10:00
Mechanically and biochemically induced pathways regulating integrin-dependent cell adhesion

Nico Strohmeyer, Switzerland
10:30
Molecular to cellular mechanics at short timescales

Felix Rico, France

11:00-11:30 COFFEE BREAK

11:30
Mechanosensitive actomyosin network dynamics and migration plasticity in 3D environments

Verena Ruprecht, Spain

Short Talks:
12:00
Activation of human aortic valve interstitial cells by local stiffness in Calcific Aortic Valve Disease

Loredana Casalis, Italy
12:15
Role of Rab8A and Caveolin-1 in the interplay between cell mechanotransduction and cholesterol trafficking
Giulio Fulgoni, Spain

12:30
The Mechanical Work of Vinculin Binding to Talin Regulates Vinculin Activation

Rafael Tapia Rojo, USA
PARÍS
10:00-12:45



BIOPHYSICS OF CYTOSKELETON
Chairs: Marisela Velez, Spain and Andreas Janshoff, Germany

I
nvited speakers:
10:00
Mind the gap: polyampholytes meet the neuronal skeleton

Roy Beck, Israel
10:30
Reconstitution of basic mitotic spindles in Cell-like confinement

Marleen Dogterom, the Netherlands

11:00-11:30 COFFEE BREAK

11:30
The spindle is a composite of two permeating polar gels

Jan Brugués, Germany

Short Talks:
12:00
Structure dissection of a contractile phage tail tube

Birgit Habenstein, France
12:15
Ultrafast tracking reveals the function of structural domains of single proteins

Kristýna Holanová, Czech Republic
12:30
Nucleotide and Osmolyte Induced Folding of FtsZ from Staphylococcus aureus

Sonia Huecas, Spain
12:45-14:30 LUNCH AND POSTER SESSION
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